PHARMACEUTICAL SCIENCES

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Advanced Pharmaceutical Techniques

Duration: 12 Weeks (12 hours per week, Total 144 Hours)

Registration Fee: INR 500

Course Fees: INR 7500

Registration End: July 15, 2020

Course Commencement: August 16, 2020

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Module 1: Overview of the Pharmaceutical Industry

  • Overview of the pharmaceutical industry and its role in the healthcare system
  • Career options in the pharmaceutical industry
  • Different functional departments and their role in the pharmaceutical industry
  • Drug Product Development
  • Calibration of Glassware
  • Preparations of Buffers and pH solutions

Module 2: Basics Concepts

  • Basic pre-formulation properties
  • Preparation and calculation of dilutions
  • Dose estimation
  • Interpretation of IR, NMR and Mass Spectrometry Graphs

Module 3: Analytical Techniques

  • UV Spectroscopy
  • HPLC
  • Dissolution

Module 4: Bio-Pharmaceutical

  • Bio-Pharmaceutical Assay
  • Qualitative assay of carbohydrate, lipids, Vitamin
  • Endpoint detection
  • Moisture content analysis
  • Viscosity
  • Assay for Herbals

Module 5: Basic and Practical Handling of Instruments

  • Homogenizer
  • Probe sonicator
  • Disintegration apparatus
  • Friability Test Apparatus
  • Rota evaporator
  • Lyophilizer
  • Electorspinner
  • Franz Diffusion
  • Orbital shaker
  • Particle size analyzer

Module 6: Formulation Development and evaluation

  • Tablet, Granules
  • Cream, Ointment
  • Lipid Vesicular system
  • Solid Dispersion
  • Nanoparticles
  • Topical Film & Patch
  • Eye Drops, Injection

Module 7: Sampling of Pharmaceutical Product and Related Materials:

  • Sampling Process.
  • Sampling Facilities.
  • Responsibility of sampling.
  • Health and Safety.
  • Classes and types of Pharmaceutical products and related materials.
  • Sampling on the recipient.
  • Sampling for Starting materials, Packing materials, and Finish products.

Module 8: Evaluation of Packing Materials:

  • Composition of packing.
  • Purpose and importance of packing material testing.
  • Package testing procedures.
  • The ideal requirement for good packaging.
  • Hazards encountered by a package.
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Prof. Abdul Wadood Siddiqui
Email: dean.pharmacy@ramauniversity.ac.in
Contact No: 9899578978

Ms. Preeti Katiyar
Email: preetikatiyar2506@gmail.com

Ms. Preeti Verma
Email: preeti.fphs@ramauiversity.ac.in

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Courseware: Course material will be provided in printed / electronic form.

Mode: Classroom presentations, Lab demos, and Hands-on Training

Eligibility: Undergraduate/ Postgraduate students of Pharmacy, Biotechnology, and Life Sciences.

Attendance Policy: 75% attendance is compulsory for the award of the certificate.

Evaluation System: Based on the post-course exam (MCQ) and Laboratory-based viva

Certification: At the end of the program the student will be awarded a certificate on successful completion of the course. (Minimum 50% score required)

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On successful completion of this course, the student will be able to:

  • Carry out analytical tests for pharmaceuticals, food products, and biologicals
  • Design and validate analytical techniques
  • Develop and optimize pharmaceutical formulations
  • Calibrate Analytical Instruments
  • Interpret analytical data
  • Prepare reports for clients/organization

 

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  • Pharmaceutical Analytical Labs
  • Food Products Analysis
  • Research & Development Centres
  • Formulation development and evaluation
  • Pharmaceutical Production
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Drug Design and Molecular Modelling

Duration: : 4 Weeks (12 hours a week, Total 48 hours)

Registration fee: INR 500

Course Fees: INR 5000

Registration End: July 31, 2020

Course Commencement: August 16, 2020

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Module 1 - Introduction to Computational Chemistry and Drug Discovery

  • Drug and Drug properties
  • Enzymes / Proteins / Receptors
  • Pharmacodynamics / Pharmacokinetics

Module 2

  • ADME rules- Drug Solubility and permeability
  • Databases
  • Target and Lead Identification/ Optimization

Module 3 - QSAR (Quantitative Structure-Activity Relationship)

  • Physicochemical aspects of Biological activity of drug and chemicals
  • SAR (Structural activity Relationship) and Applications of QSAR
  • Chemical information and descriptors
  • Statistical Methods in QSAR - MLR / PLS / PCA / ANN
  • Validation of QSAR models - Internal and External validation
  • End of the module with practices

Module 4 - Molecular Modeling / Docking Concepts

  • Structure-Based Drug Design
  • Structural based screening method Structure-based hit identification End of the module with practices
  • Ligand Based Drug Design
  • Ligand-based screening method Ligand-based hit identification End of the module with practices
  • Statistical studies
  • ADMET prediction by QikProp 3.3
  • Validation of target Enrichment studies Parameter based screening MMGBSA (Binding energy calculation) Selection of lead molecule

Module 5

  • Simulation Study
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Dr. Abdul Wadood Siddiqui
Email: dean.pharmacy@ramauniversity.ac.in
Contact No: 9899578978

Dr. Amit Kumar Keshari
Email: amitkumar.fphs@ramauniversity.ac.in
Contact No: 7054090169

Ms. Preeti Verma
Email: preeti.fphs@ramauiversity.ac.in

Mrs. Sneha Kushwaha

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Courseware: Course material will be provided in printed or electronic form

Mode of Teaching : Classroom and CADD Lab

Required Softwares: Autodock Vina Discovery, Studio Visualiser, ChemDraw Ultra 13, Maestro, Shrodinger, Database PDB, Drugbank, Zincpharmer Structure Database - NCBI, PDB

Intended Audience: Pharmaceuticals/ Biotech / Bioinformatics /Chemistry and allied programs, pharma industries, and researchers.

Prerequisites: Prior knowledge of biochemistry and bioinformatics. Students should be able to identify organic chemistry functional groups and chemical structures. Students should also know the parts of a cell and be comfortable working with mathematical expressions containing exponents and logarithms.

Attendance Criteria: 100 % in practical and 80% in theory

Evaluation System: MCQs on QSAR and molecular modeling (100 marks)

Certification: Certificate of participation will be provided at the end of the course (Minimum 60% score required)

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  • The student will be able to relate the chemical structure of a drug to its biological function.
  • Students will be able to attend lectures on drug discovery and reasonably understand the content of the lectures.
  • The Course content meets the industry standards.
  • The participants will gain knowledge of computational drug design.
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Data Scientist in Industries /Labs

  • Research Associate in Medicinal Chemistry
  • Project Assistant
  • Professorship- Drug Discovery and Medicinal Chemistry
  • Bioinformaticist in the health sector
  • Postdoctoral positions
  • Computational Biophysicists
  • Business Development Executive
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Experimental Pharmacology by Software

Duration: 4 weeks, 6 Hours per week, Total 24 Hours

Registration Fee: INR 100

Course Fees: INR 1500

Registration End: July 31, 2020

Course Commencement: August 16, 2020

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COURSE CONTENT

  • Study of muscle relaxant activity with the help of “Rota-Rod Apparatus”.
  • Study of CNS depressants & stimulants using "actophotometer".
  • Study of analgesic activity with the help of a "tail-flick apparatus".
  • Study of antihistaminic drugs with the help of the histamine chamber.
  • Study of analgesic activity with the help of a "hot plate apparatus".
  • Study of drugs acting on CNS using "elevated plus maze".
  • Study of anticonvulsant activity using "electro covulsiometer".
  • Experiment on the effects of various drugs on the rabbit's eye.
  • To study analgesic activity by writhing test.
  • To study PTZ induced convulsions in mice
  • Effect of different drugs on frog's heart
  • Experiment on bioassay of histamine on the ileum of guinea pig
  • Effect of adrenaline, acetylcholine, and atropine on dog arterial pressure.
  • Experiments on rat BP
  • Experiments of rat blood sugar
  • To record the dose-response curve and to determine the PD2 value for acetylcholine on the frog rectus abdominal muscle.
  • Study of diuretic activity using metabolic cage
  • Study of anti-inflammatory activity using carrageenan-induced paw edema method
  • Bioassay of oxytocin on the isolated rat uterine horn
  • Bioassay of serotonin on the isolated rat fundus strip
  • Rabbit Pyrogen Test
  • Effects of drugs on the dog BP and Heart Rate
  • Effects of drugs on the ciliary motility of frog esophagus 

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Mr. Nishant Singh Katiyar
Email: nishantkatiyar.fphs@ramauniversity.ac.in
Contact No: 9455076190


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Courseware: Course material is provided in printed / electronic form.

Mode: Classroom and computer lab training.

Eligibility: Undergraduate/ Postgraduate students of Pharmacy, Nursing, Biotechnology, and Zoology.

Attendance Policy: 75% attendance is compulsory for the award of the certificate.

Evaluation System: Based on the post-course exam (MCQ)


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On successful completion of this course the students will be able:

  • To understand the effect of drugs on animals by simulated experiments
  • To understand the effects of drugs on isolated animal tissues by simulated experiments.
  • To understood the concepts of drug action and mechanisms involved.
  • To understand the importance of isolated preparation, mechanism of action of drugs on isolated tissues, expertise in performing bioassay of drugs.
  • To understand the drug antagonism using isolated tissue preparations.
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Pharmacology is a broad sector and students (participants) will develop skills in experimental pharmacology for getting a job in the industry and governmental research and development sector as a: 

 

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Pharma Industry Laboratory Skills

Duration: 60 Hours (The training is divided into 5 modules. Each module shall be of 12 hours duration )

Registration Fee: INR 500

Course Fees: INR 5000

Registration End: July 31, 2020

Course Commencement: August 16, 2020


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Module 1: Safe Laboratory Operations

  • Why laboratory safety deserves the highest priority.
  • Safety symbols and safety gear.
  • Hazard properties and safe handling of laboratory chemicals.
  • Safe handling of laboratory glassware.
  • Safe handling of laboratory instruments.
  • Laboratory fire hazards prevention and control.
  • Elementary laboratory first aid.

 

Module 2: Environmental Controls in Laboratories

  • Significance of Cleanliness and Hygiene in laboratories.
  • Monitoring and control of temperature and humidity.
  • Laboratory waste disposal.
  • Laboratory spills management.

 

Module 3: Sample Handling and Minimization of Analytical Errors

  • Common units of analytical measurements.
  • Sample preservation and management.
  • Volumetric glassware grades and calibration.
  • Analytical method validation.
  • Essential precautions in dilutions and titrimetric analysis.
  • Precautions in common laboratory determinations.

 

Module 4: Laboratory Standards and Reference Materials

  • Primary and secondary laboratory standards.
  • Revalidation of working standards.
  • GLP and GDP.
  • CAPA and uncertainty of measurements.
  • Importance of calibration and record maintenance.

 

Module 5: Assurance of Quality of Results to Internal and External Customers

  • Difference between Quality Assurance and Quality Control.
  • Need for replicate analysis
  • Internal laboratory audits.
  • Customer feedback review for improvement of laboratory service.

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Prof. Abdul Wadood Siddiqui
Email: dean.pharmacy@ramauniversity.ac.in
Contact No: 9899578978

Ms. Preeti Verma
Email: preeti.fphs@ramauiversity.ac.in

Ms. Pratiksha Jayaswal
Email: pratiksha.fphs@ramauniversity.ac.in

Ms. Preeti Katiyar
Email: preetikatiyar2506@gmail.com

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Courseware: Course material is provided in printed / electronic form.

Mode: Classroom presentation, lab demos, and hands-on training.

Eligibility: D.Pharma, B.Pharma, M.Phrama, Biotechnology, B.Sc., M.Sc., and Life sciences students can enroll

Attendance Policy: 75% attendance is compulsory for the award of the certificate.

Evaluation System:  Based on the post-course exam ( MCQ ) and laboratory-based viva.

Certification: At the end of the program students will b awarded a certificate on successful completion of the course (min. 50 % score required).


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After completing this course the student will be able to:

  • Carry out Chemical, physical and instrumental analysis.
  • Analytical tests for pharmaceuticals, food products, and biological products.
  • Pharmaceutical product control sampling.
  • Design and validate analytical techniques.
  • Calibrate Analytical Instruments.
  • Interpret analytical data.
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  • Commercial Testing Laboratories.
  • Pharma and Food industries.
  • Referral laboratories such as BIS, IPC.
  • R&D laboratories in pharma and life sciences.
  • Environmental monitoring and control laboratories.
  • Forensic laboratories.
  • Clinical Testing laboratories.

 

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Pharmaceutical Pre-formulation Studies for Formulation Development

Duration: 4 Weeks, 60 hours

Registration Fee: INR 200

Course Fees: INR 800

Registration End: July 31, 2020

Course Commencement: August 16, 2020


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Module-1. Introduction to Pharmaceutical Formulation

Module-2. Role of Preformulation Studies in Drug Discovery

Module-3. Role of Preformulation Studies in Drug Development

Module-4. Aqueous solubility

Module-5. Permeability

Module-6. Stability Studies

Module-7. Solid-State Properties

Module-8. Compaction Studies

Module-9. Compatibility Studies

Module-10. Pre-Formulation Report


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Ms. Priya Tiwari
Email: priyatiwari.fphs@ramauniversity.ac.in

Ms. Pratiksha Jayaswal
Email: pratiksha.fphs@ramauniversity.ac.in

Mr. Peeyush
Email: Peeyush.fphs@ramauniversity.ac.in
Contact No: 9532674131


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Courseware: Course material is provided in printed / electronic form.

Mode of Teaching: Classroom and Laboratory exercises (Lab demos and Hands-on Training)

Eligibility: Any student from B. Pharm/ M. Pharm. or other Life Sciences streams

Note: Limited seats are available. Registration will be on a first come and first serve basis.

Attendance Policy: 75% attendance is compulsory for the award of the certificate.

Evaluation System: MCQ quiz after each module.

Certification: Certificate will be provided after completion of the course (Score at least 60% to pass.)


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  • To understand the Dosage forms and their various manufacturing techniques.
  • To understand all the related and practical aspects of dosage form development.
  • To formulate and evaluate the dosage forms like solid, liquid, and semisolid dosage forms. 
  • To correlate the theoretical knowledge with the professional and practical needs of the Pharmaceutical industry.

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  • Molecular modification
  • Quality control
  • Clinical research
  • Formulation development and evaluation
  • Pharmaceutical Production

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Standardization of Herbal Drugs

Duration: 6 Weeks (12 Hours per week, Total 72 Hours)

Registration Fee: INR 500

Course Fees: INR 7500

Registration End: July 31, 2020

Course Commencement: August 16, 2020.


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Module 1: Introduction of standardization and role
Raw material
Finished products
Need of standardization
Problems In standardization
WHO guidelines
Career options in the herbal pharmaceutical industry

Module 2: Botanical parameters
Macroscopy (Organoleptic characteristics)
Microscopic characteristics
Foreign matter analysis

Module 3: Physico-chemical parameters
Extractive values
Ash values
Loss on drying/Moisture content
Volatile matter

Module 4: General parameters
Fluorescent analysis,
Powdered drug reaction with different reagent,
Phytochemical screening,
Determination of pH,
Determination of resin content,
Determination of fat content
Phenolic content

Module 5: Pharmacological parameters
Swelling index
Toxicological contaminants:
Arsenic and Heavy metals,
Pesticide residues,
Microbial load,
Aflatoxins

Module 6: Biological Evaluation & TLC fingerprinting analysis
Antidiabetic activity
TLC fingerprinting analysis / Quantification of active ingredients

 

 


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Dr. Kamran Javed Naquvi
Email: kamranjaved.fphs@ramauniversity.ac.in


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Courseware: Course material will be provided in printed / electronic form.

Mode: Classroom presentations, Lab demos, and Hands-on Training

Eligibility: 10+2 perusing D.Pharm/ B.Pharm/ Biotech; B.Sc. (Biology)/ Agriculture Sciences etc.

Attendance Policy: 75% attendance is compulsory for the award of the certificate.

Evaluation System: Based on post-course exam (MCQ) and Laboratory-based viva

Certification: At the end of the program the student will be awarded a certificate on successful completion of course. (Minimum 50% score required)

 


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After completing this course the student will be able to:

  • Understand the various parameters of the standardization of herbal drugs.
  • Carry out the morphological, microscopical, Physico-chemical, biological evaluation of crude drugs.
  • Carry out the evaluation of crude drugs.
  • Skilled in the isolation of volatile oil and to carryout TLC analysis along with quantification of active ingredients.
  • Skilled in the evaluation of herbal drugs/finished products in the herbal industries and government research organizations.

Prepare reports for clients/ organizations

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  • Private/government herbal research organizations and labs. 
  • AYUSH (Ministry of AYUSH, Government of India)
  • Central Council for Research in Unani Medicines (CCRUM)
  • Indian Council of Medical Research (ICMR)
  • Central Council for Research in Ayurvedic Sciences (CCRAS) 
  • Ayurvedic/Unani/Homeopathic industries.

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